Scientists find clue to stop brain tumor growth

Hii, I am hervinder singh. today I have noticed that one person in group three person is facing the brain tumor problem. and there is no solution to solve the brain tumor growth ,surgery was only the single option.Now in
Washington, Scientists have discovered a pathway between deadly cancerous cells which they believe could be blocked to inhibit their growth and malignancy. 


An international team of scientists at the Ludwig Institute for Cancer Research (LICR) at the University of California claimed that they have found a new signalling pathway between glioblastoma multiforme (GBM) cells -- the most aggressive form of malignant glioma, or brain tumour, cells. 

This cells is the major reason of tumor growth. Now, in reasearch, 
According to scientists, more than other types of cancer, GBMs are diverse assemblages of cell subtypes featuring great genetic variation. Anti-cancer therapies that target a specific mutation or cellular pathway tend to be less effective against such tumour heterogeneity.

"These myriad genetic alterations may be one of the primary reasons why GBMs are so lethal," said Frank Furnari, a professor of medicine at LICR and co-author of the study.

Even with maximum treatment effort, the median patient survival rate for a diagnosed GBM is nine to 12 months -- a statistic that has not changed substantially in decades, he said.

However, Furnari and his colleagues noted that in GBMs only a minority of tumour cells possess a mutant form of the epidermal growth factor receptor (EGFR) gene. These cells drive the tumour's rapid, deadly growth.

Furnari said: "Most GBM tumor cells express wild-type or normal EGFR. Yet when expressed by itself, wild-type EGFR is a poor oncogene."

"The mutant cells are instructing other less malignant tumour cells to become more malignant," he said, adding this signalling pathway between GBM tumour cells was not known and presents a new and potentially promising chink in the armour of glioblastomas.

"If we can inhibit or block this cellular communication, the tumour does not grow as quickly and may be more treatable," Furnari said.

So, medical science are coming up with new invention, but doing that particular things we can find a new solution and human lifetime may be increased by stopping these type of diseases causing serious results.